What are the cures for Hemophilia?
Saturday, June 9, 2012
3:00 PM



CURES

1) GENE THERAPY

The current possible cure for hemophilia is gene therapy.  As hemophilia is caused by the lack of blood clotting proteins (usually factor 8 or factor 9), gene therapy is to aim to produce enough of these protein to reverse the effect of hemophilia.  


Gene therapy works by removing cells with hemophilia and alter the cells genetically which do not cause hemophilia. They usually use liver cells but other kinds of cells are also proven successful. Cells are then reprogrammed by inserting new genetic materials. The new materials allow the cell to produce factor 8 and 9 blood clotting proteins now which is then reinserted back into the patient. The cells multiply and take over the others which allow the patient to be hemophilia-free now. The processes are still being perfected and are still under researches.


        

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2)  PROPHYLAXIS/REPLACEMENT THERAPY





Examples of commerically produced factors. 




Hemophiliacs have to inject themselves with artifically produced clotting factors every few days. The regular infusion of clotting factors into their body allow the clotting levels to be fairly high to prevent extreme spontaneous bleeding episodes. Recombinant clotting factors are preferred over extracted clotting factors due to it's high purity and safety. However, it is very expensive which usually only allow developed countries to be available with it.


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LINKS:
 http://www.hemophilia-information.com/Cure-for-hemophilia.html
http://www.mayoclinic.com/health/hemophilia/ds00218/dsection=treatments-and-drugs
http://www.news-medical.net/health/Haemophilia-Treatments.aspx

        
http://www.aetna.com/cpb/medical/data/100_199/0131.html 

http://www.aetna.com/cpb/medical/data/100_199/0131.html


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Haemophilia
❝ A Blood Disease ❞


Jacqueline
Joey
BMS 2M05
,
18, Ngee Ann Poly.
Feel free to read around, if u have any questions just write in the chatbox.






LYRICS
(Verse 1)
The story starts when I was born.
The doctors said I was not the norm.
X chromosomes that are infected.
I get a cut - platelets can't detect it.

(Chorus)
I have a very rare disease.
I can't fall down or I'll scrape my knees.
If you find a cure, won't you set me free?
Hemophilia is killing me.

(Verse 2)
Plasma is one thing that makes up blood.
Deficiencies can cause your cuts to flood.
Got it from mom - no clotting factor 8.
Not good at sports - I guess it was fate.

(Chorus)
I have a very rare disease.
I can't fall down or I'll scrape my knees.
If you find a cure, won't you set me free?
Hemophilia is killing me.

(Verse 3)
If you're a male your odds are 1 in 5,000.
But don't get scared, this number is rounded.
Bleeding won't stop unless I get an infusion.
One time when I was three, I was riding my skateboard and I hit a rock and fell off and there was a pool of blood then my parents came running outside and there was a lot of confusion.
(Chorus)
I have a very rare disease.
I can't fall down or I'll scrape my knees.
If you find a cure, won't you set me free?
Hemophilia is killing me.






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